SENNA (CASSIA ANGUSTIFOLIA) OTHER NAME(S): Alexandrian Senna, Alexandrinische Senna, Casse, Cassia acutifolia, Cassia angustifolia, Cassia lanceolata, Cassia senna, Fan Xie Ye, Indian Senna, Khartoum Senna, Sen, Sena Alejandrina, Séné, Séné d’Alexandrie, Séné d’Egypte, Séne d’Inde, Séné de Tinnevelly, Senna alexandrina, Sennae Folium, Sennae Fructus, Sennosides, Tinnevelly Senna, True Senna. Introduction Senna is a popular herbal laxative that is available without prescription. Senna is generally safe and well tolerated, but can cause adverse events including clinically apparent liver injury when used in high doses for longer than recommended periods. Background Senna is an herb, and senna tea is made from the leaves of the Cassia senna plant. These plants thrive in tropical areas, though some can grow in more temperate climates. Senna tea can be slightly sweet, but it has strong bitter undertones. Because of this, people sometimes mix senna tea with green tea or add honey to improve its flavor. It is also not incredibly aromatic. Senna tea has been marketed as a constipation treatment and a “detox” tea. It’s also often used as a weight loss aid, although this is not recommended. Thanks to its ability to treat constipation, it’s sometimes used short-term to treat hemorrhoids. However, there is insufficient evidence to support the use of senna for hemorrhoids or weight loss. Senna is approved by the FDA as a nonprescription laxative.